The risk for developing diabetes follows a continuum. The higher your blood sugar level, the greater the chance that you will subsequently develop diabetes.
If your fasting blood glucose is between 100 mg/dL and 126 mg/dL, you have what's known as pre-diabetes. (A fasting blood sugar level of 126 mg/dL is defined as diabetes.) A large number of Nigerians have pre-diabetes and, therefore, are much more prone to developing diabetes. Like people with diabetes, those with pre-diabetes tend to be overweight, have high blood pressure and abnormal cholesterol levels, and have a higher risk for cardiovascular disease.
Fat is more than just a storage site for extra nutrients in the body. Fat, also functions as an endocrine organ, producing hormones that affect appetite and insulin action.
So far, scientists have found that fat cells produce the hormones leptin, resistin, and adiponectin. Leptin is normally released after a meal and dampens appetite. Resistin and adiponectin both affect cells' response to insulin. (Too much resisting may cause insulin resistance; too little adiponectin may do the same.) Although the appetite regulation system is complex and scientists are still deciphering the roles of individual hormones, it's becoming clear that excess body fat disrupts the normal balance and functioning of these hormones, thereby contributing to insulin resistance and setting the stage for diabetes.
Fat location also matters
The risk of added kilograms is especially high when the excess weight is distributed around the stomach—often referred to as an "apple" shape—as opposed to around the hips, called the "pear" shape. Excess weight around the waist also puts you at risk for a condition known as metabolic syndrome.
Fat can accumulate both under the skin (known as subcutaneous fat) and around the abdominal organs (known as visceral fat). A large belly suggests the presence of this harmful fat, which produces hormones called cytokines that contribute to insulin resistance.
Visceral fat may affect levels of glucocorticoids, steroid hormones that also contribute to obesity and insulin resistance. Furthermore, fatty acids (the breakdown products of fat) may play a direct role in insulin resistance when they are distributed in muscle, making muscle more resistant to insulin's action.It is becoming clearer that fat—especially abdominal fat—adversely affects insulin action and contributes to the development of diabetes.
Stomach Fat is Very Bad Fat!
Dr Dileem
The Likita Bokanturai
Kano Nigeria
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